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ARRY-520 (R) 30002 Tissue distribution of BLU-554 (10

ARRY-520 (R) 30002 Tissue distribution of BLU-554 (10

Name: ARRY-520 (R) 30002 Tissue distribution of BLU-554 (10
Brand: firemistltd.co.uk
SKU: 95554640249
Price: 100.00 USD
Availability: InStock
Rating: 4.5391 (10 reviews)

SKU: 95554640249

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SEK100.00 SEK144.00

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ARRY-520 (R) 30002 Tissue distribution of BLU-554 (10ARRY 520 R enantiomer is the R form of ARRY 520, which is a synthetic, small molecule kinesin spindle protein (KSP) inhibitor. ARRY 520 had low nanomolar antiproliferative activity in tumor cell lines and specifically inhibits KSP (kinesin 5 or Eg5), resulting in activation of the spindle assembly checkpoint, induction of cell cycle arrest during the mitotic phase, and consequently cell death in tumor cells that are actively dividing. Product

Store: firemistltd.co.uk · Domain: firemistltd.co.uk

Description

Tissue distribution of BLU-554 (10 mg/kg

TH588 was dosed to the mice by subcutaneous administration at 30 mg/kg once per day for 21 days

4% Tween-80

reduction of oxidative stress

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