NMS-1286937 Catalog No.:M9125-2 Chemical Name: (2E)-but-2-enedioic acid

Chemical Name: (2E)-but-2-enedioic acid

Selective TGF-β1/ALK inhibitor improves neuronal differentiation of mouse embryonic stem cells

Ibandronate is indicated for the treatment and prevention of osteoporosis in post-menopausal women

Formula: C10H10N2O

NMS-1286937 Catalog No.:M9125-2 Chemical Name: (2E)-but-2-enedioic acidOnvansertib, also know as NMS P937, PCM 075 and NMS1286937, is a n orally bioavailable, small molecule Polo like kinase 1 (PLK1) inhibitor with potential antineoplastic activity. Polo like kinase 1 inhibitor NMS 1286937 selectively inhibits PLK1, inducing selective G2 M cell cycle arrest followed by apoptosis in a variety of tumor cells while causing reversible cell cycle arrest at the G1 and G2 stages without apoptosis in normal cells. PLK1