AZD2858 46040 which is comparable with the

which is comparable with the response seen with activated wt mALK

4-dihydroxy-6-methyl-5-{[(1S

InChi: InChI=1S/C29H30N8O5/c1-2-37-24-17-25(31-18-23(24)33-28(37)26-27(30)35-42-34-26)41-22-5-3-4-20(16-22)32-29(38)19-6-8-21(9-7-19)40-15-12-36-10-13-39-14-11-36/h3-9

Smiles: CC1=C(CC(O)=O)C2=CC=CN=C2N1CC1=CC=C(C=C1C(F)(F)F)S(C)(=O)=O

AZD2858 46040 which is comparable with theAZD2858 is a potent and GSK 3 inhibitor with an IC50 of 68 nM. AZD 2858 inhibits tau phosphorylation at the S396 site, and it activates Wnt signaling pathway. AZD2858 has a substantial impact on fracture healing. The fractures healed with a bony callus without an obvious endochondral component, suggesting that AZD2858 drives mesenchymal cells into the osteoblastic pathway. Product information CAS Number: 486424 20 8 Molecular Weight: 453. 52 Formula: