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SB 415286 astatin PubMed PMID: 23370664

SKU: 72648147376

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SEK108.00 SEK158.00

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SB 415286 astatin PubMed PMID: 23370664SB 415286 is a potent and selective cell permeable, ATP competitive inhibitor of GSK3 with an IC50 value of 78 nM (similar potency for GSK3) and a Ki value of 31 nM. Pharmacological GSK 3 inhibitors are potential drugs for the treatment of neurodegenerative diseases, cancer and diabetes. Product information CAS Number: 264218 23 7 Molecular Weight: 359. 72 Formula: C16H10ClN3O5 Chemical Name: 3 [(3 chloro 4 hydroxyphenyl)amino] 4 (2 nitrophenyl) 2,5

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PubMed PMID: 23370664

3-d]pyrimidin-4-amine

although removing Top1 was itself eventually toxic

2017 Oct 30

SB 415286 astatin PubMed PMID: 23370664SB 415286 is a potent and selective cell permeable, ATP competitive inhibitor of GSK3 with an IC50 value of 78 nM (similar potency for GSK3) and a Ki value of 31 nM. Pharmacological GSK 3 inhibitors are potential drugs for the treatment of neurodegenerative diseases, cancer and diabetes. Product information CAS Number: 264218 23 7 Molecular Weight: 359. 72 Formula: C16H10ClN3O5 Chemical Name: 3 [(3 chloro 4 hydroxyphenyl)amino] 4 (2 nitrophenyl) 2,5

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