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Pemetrexed (disodium) ium (Chloride) InChi: InChI=1S/C21H23Cl2N5O/c22-15-3-1-4-16(23)14(15)11-28-9-7-13(8-10-28)12-29-18-6-2-5-17-19(18)20(24)27-21(25)26-17/h1-6

Pemetrexed (disodium) ium (Chloride) InChi: InChI=1S/C21H23Cl2N5O/c22-15-3-1-4-16(23)14(15)11-28-9-7-13(8-10-28)12-29-18-6-2-5-17-19(18)20(24)27-21(25)26-17/h1-6

Name: Pemetrexed (disodium) ium (Chloride) InChi: InChI=1S/C21H23Cl2N5O/c22-15-3-1-4-16(23)14(15)11-28-9-7-13(8-10-28)12-29-18-6-2-5-17-19(18)20(24)27-21(25)26-17/h1-6
Brand: firemistltd.co.uk
SKU: 58092621665
Price: 75.00 USD
Availability: InStock
Rating: 4.0342 (19 reviews)

SKU: 58092621665

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Pemetrexed (disodium) ium (Chloride) InChi: InChI=1S/C21H23Cl2N5O/c22-15-3-1-4-16(23)14(15)11-28-9-7-13(8-10-28)12-29-18-6-2-5-17-19(18)20(24)27-21(25)26-17/h1-6Pemtrexed disodium is the disodium salt of a synthetic pyrimidine based antifolate. Pemetrexed binds to and inhibits the enzyme thymidylate synthase (TS) which catalyses the methylation of 2' deoxyuridine 5' monophosphate (dUMP) to 2' deoxythymidine 5' monophosphate (dTMP), an essential precursor in DNA synthesis. Product information CAS Number: 150399 23 8 Molecular Weight: 471. 37 Formula: C20H19N5Na2O6 Synonym: LY231514 disodium Alimta disodium LY

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Description

InChi: InChI=1S/C21H23Cl2N5O/c22-15-3-1-4-16(23)14(15)11-28-9-7-13(8-10-28)12-29-18-6-2-5-17-19(18)20(24)27-21(25)26-17/h1-6

Chemical Name: 1-(4-((dimethylamino)methyl)phenyl)-8

When applied to acute hippocampal slices

Y-33075 (Y-39983) is a potent ROCK inhibitor

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