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ICRT-14 - CAS# 677331-12-3 Catalog No.:M6516-C Different from AZD8055

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ICRT-14 - CAS# 677331-12-3 Catalog No.:M6516-C Different from AZD8055ICRT 14, CAS No. 677331 12 3, is a potent inhibitor of catenin responsive transcription (CRT) that inhibits Wnt signaling in a reporter assay in vitro (IC50 = 40. 3 nM). It inhibits the interaction between catenin and T cell factor 4 (Tcf4) in quantitative reporter assays of catenin Tcf4 binding (Ki = 53. 51 M). Product information CAS Number: 677331 12 3 Molecular Weight: 375. 44 Formula: C21H17N3O2S Synonym: iCRT14 iCRT 14 iCRT 14 Wnt inhibitor

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Description

Different from AZD8055

and Maver-1) xenograft animal models orally at 200 mg/Kg once per day

Smiles: C[C@]12CC[C@H](O)CC1=CC[C@@H]1[C@@H]2CC2[C@H]1CC[C@]1(O[C@@H]3C[C@H](C)CN[C@H]3[C@H]1C)C=2C

(2008) Biochem Biophys Res Commun

ICRT-14 - CAS# 677331-12-3 Catalog No.:M6516-C Different from AZD8055ICRT 14, CAS No. 677331 12 3, is a potent inhibitor of catenin responsive transcription (CRT) that inhibits Wnt signaling in a reporter assay in vitro (IC50 = 40. 3 nM). It inhibits the interaction between catenin and T cell factor 4 (Tcf4) in quantitative reporter assays of catenin Tcf4 binding (Ki = 53. 51 M). Product information CAS Number: 677331 12 3 Molecular Weight: 375. 44 Formula: C21H17N3O2S Synonym: iCRT14 iCRT 14 iCRT 14 Wnt inhibitor

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