Apilimod - CAS# 541550-19-0 Size:Solid 10 mg N-bis(2-chloroethyl)-4-(3-{6-[6-(4-methylpiperazin-1-yl)-1H-1

N-bis(2-chloroethyl)-4-(3-{6-[6-(4-methylpiperazin-1-yl)-1H-1

3)20(30-24(37)31-26(4

Sensitivity of imatinib-resistant T315I BCR-ABL CML to a synergistic combination of ponatinib and forskolin treatment

is a potent and irreversible small-molecule inhibitor of FGFR4

Apilimod - CAS# 541550-19-0 Size:Solid 10 mg N-bis(2-chloroethyl)-4-(3-{6-[6-(4-methylpiperazin-1-yl)-1H-1Apilimod, also known as STA 5326, is a IL 12 IL 23 inhibitor. Apilimod inhibits IL 12 and IL 23 production cytokines that are involved in autoimmune diseases through the prevention of nuclear translocation of c Rel. Synta Pharmaceuticals Corp is developing apilimod for the potential treatment of Crohn's disease (CD) and other autoimmune diseases. Preclinical studies demonstrated the successful inhibition of IL 12 and IL 23 production by the drug.