Eltrombopag (Olamine) ntherin A Homo-PROTAC pVHL30 degrader 1
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Eltrombopag (Olamine) ntherin A Homo-PROTAC pVHL30 degrader 1Eltrombopag is a small molecule, nonpeptide thrombopoietin receptor agonist with megakaryopoiesis stimulating activity. Eltrombopag binds to and stimulates the transmembrane domain of the platelet thrombopoietin receptor (TPO R or CD110), a member of the hematopoietin receptor superfamily. Activation of TPO R leads to the proliferation and differentiation of cells in the megakaryocytic lineage and an increase in platelet production. Eltrombopag was
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