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AMG-208 - CAS# 1002304-34-8 K-4827 Tosylate CAS Number: 131875-08-6

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AMG-208 - CAS# 1002304-34-8 K-4827 Tosylate CAS Number: 131875-08-6AMG 208 is a selective small molecule inhibitor of the proto oncogene c Met with potential antineoplastic activity. c Met inhibitor AMG 208 inhibits the ligand dependent and ligand independent activation of c Met, inhibiting its tyrosine kinase activity, which may result in cell growth inhibition in tumors that overexpress c Met. C Met encodes the hepatocyte growth factor receptor tyrosine kinase, plays an important role in epithelial cell

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Description

CAS Number: 131875-08-6

3-dihydro-1-benzofuran-4-yl)methyl]-8-(2-methylpyridin-3-yl)-[1

144(3):361-72

11aS)-10-[4-(dimethylamino)phenyl]-1-hydroxy-11a-methyl-1-(prop-1-yn-1-yl)-1H

AMG-208 - CAS# 1002304-34-8 K-4827 Tosylate CAS Number: 131875-08-6AMG 208 is a selective small molecule inhibitor of the proto oncogene c Met with potential antineoplastic activity. c Met inhibitor AMG 208 inhibits the ligand dependent and ligand independent activation of c Met, inhibiting its tyrosine kinase activity, which may result in cell growth inhibition in tumors that overexpress c Met. C Met encodes the hepatocyte growth factor receptor tyrosine kinase, plays an important role in epithelial cell

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