Human Toll-like Receptor 1, TLR1 ELISA Kit , 96T Tubes G Protein-Coupled Receptor 176 is

G Protein-Coupled Receptor 176 is a orphan receptor

The protein localizes to actin-rich structures including membrane ruffles| microvilli| and filopodia

Likely to power actin-based membrane trafficking in many physiologically crucial tissues

|Contains 1 acyl carrier domain

Human Toll-like Receptor 1, TLR1 ELISA Kit , 96T Tubes G Protein-Coupled Receptor 176 isParticipates in the innate immune response to microbial agents. Specifically recognizes diacylated and triacylated lipopeptides. Cooperates with TLR2 to mediate the innate immune response to bacterial lipoproteins or lipopeptides (PubMed: 21078852). Forms the activation cluster TLR2: TLR1: CD14 in response to triacylated lipopeptides, this cluster triggers signaling from the cell surface and subsequently is targeted to the Golgi in a lipid raft