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c-Abl(Phospho-Tyr89) Rabbit Polyclonal Antibody, 50ul Hepatocytes The encoded protein is activated

SKU: 98648941794

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c-Abl(Phospho-Tyr89) Rabbit Polyclonal Antibody, 50ul Hepatocytes The encoded protein is activatedThis gene is a protooncogene that encodes a protein tyrosine kinase involved in a variety of cellular processes including cell division adhesion differentiation and response to stress. The activity of the protein is negatively regulated by its SH3 domain whereby deletion of the region encoding this domain results in an oncogene. The ubiquitously expressed protein has DNA binding activity that is regulated by CDC2 mediated phosphorylation suggesting a

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Description

The encoded protein is activated in mitosis and

The encoded protein maybe play a role in the ability of the replication fork to bypass DNA lesions

Expression of this gene has been found to be upregulated in small cell lung cancers

cell-cell adhesion

c-Abl(Phospho-Tyr89) Rabbit Polyclonal Antibody, 50ul Hepatocytes The encoded protein is activatedThis gene is a protooncogene that encodes a protein tyrosine kinase involved in a variety of cellular processes including cell division adhesion differentiation and response to stress. The activity of the protein is negatively regulated by its SH3 domain whereby deletion of the region encoding this domain results in an oncogene. The ubiquitously expressed protein has DNA binding activity that is regulated by CDC2 mediated phosphorylation suggesting a

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