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PLK2 Polyclonal Antibody, 100ul High Speed Micro-Centrifuges Mutations in this gene have

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PLK2 Polyclonal Antibody, 100ul High Speed Micro-Centrifuges Mutations in this gene haveThe protein encoded by this gene is a member of the polo family of serine threonine protein kinases that have a role in normal cell division. This gene is most abundantly expressed in testis, spleen and fetal tissues, and its expression is inducible by serum, suggesting that it may also play an important role in cells undergoing rapid cell division. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

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Description

Mutations in this gene have been associated with primary pulmonary hypertension

Diseases associated with MYF5 include skeletal muscle cancer and botryoid rhabdomyosarcoma

which is characterized by two motifs in the C-terminal half of the protein: a basic region involved in DNA binding and a leucine zipper motif involved in dimerization

and recombination

PLK2 Polyclonal Antibody, 100ul High Speed Micro-Centrifuges Mutations in this gene haveThe protein encoded by this gene is a member of the polo family of serine threonine protein kinases that have a role in normal cell division. This gene is most abundantly expressed in testis, spleen and fetal tissues, and its expression is inducible by serum, suggesting that it may also play an important role in cells undergoing rapid cell division. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

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