MARCH2 Polyclonal Antibody, 100ul Recombinant Protein Defects in this gene are

Defects in this gene are a cause of Townes-Brocks syndrome (TBS) as well as bronchio-oto-renal syndrome (BOR)

This intronless gene is deleted in AMME contiguous gene syndrome and may be involved in the cardiac and neurologic abnormalities found in the AMME contiguous gene syndrome

Voltage-sensitive calcium channels mediate the entry of calcium ions into excitable cells

RHOA encodes a member of the Rho family of small GTPases

MARCH2 Polyclonal Antibody, 100ul Recombinant Protein Defects in this gene areMARCH2 (membrane associated ring CH type finger 2) is a member of the MARCH family of membrane bound E3 ubiquitin ligases. MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH2 reduces surface accumulation of several glycoproteins and appears to regulate early endosome to trans Golgi network (TGN) trafficking.