SPB8 Polyclonal Antibody, 100ul Deep Well Plates Defects in this gene results

Defects in this gene results in hemophilia A

but not for neutrophils

This protein and ATM share similarity with Schizosaccharomyces pombe rad3| a cell cycle checkpoint gene required for cell cycle arrest and DNA damage repair in response to DNA damage

Contains 1 Sema domain

SPB8 Polyclonal Antibody, 100ul Deep Well Plates Defects in this gene resultsThe superfamily of high molecular weight serine proteinase inhibitors (serpins) regulate a diverse set of intracellular and extracellular processes such as complement activation, fibrinolysis, coagulation, cellular differentiation, tumor suppression, apoptosis, and cell migration. Serpins are characterized by well conserved a tertiary structure that consists of 3 beta sheets and 8 or 9 alpha helices (Huber and Carrell, 1989