PDHK1(Phospho Tyr243) Rabbit Polyclonal Antibody, 100ul[BT-AP11861] Cryogenic Vials Plays a key role in

Plays a key role in the antiproliferative action of IFN-gamma either by inhibiting the ERK activition or by arresting cell growth in G1 phase in a p53-dependent manner

Transcript variants derived from alternative promoter usage and/or alternative splicing exist

cofactor:Binds 1 zinc ion per subunit

Three phosphofructokinase isozymes exist in humans: muscle

PDHK1(Phospho Tyr243) Rabbit Polyclonal Antibody, 100ul[BT-AP11861] Cryogenic Vials Plays a key role inPyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. The enzymatic activity is regulated by a phosphorylation dephosphorylation cycle. Phosphorylation of PDH by a specific pyruvate dehydrogenase kinase (PDK) results in inactivation. Multiple alternatively spliced