Beta-Catenin Polyclonal Antibody, 50ul Organelle Studies USP45 (Ubiquitin carboxyl-terminal hydrolase 45)

USP45 (Ubiquitin carboxyl-terminal hydrolase 45)

Combined with high-throughput sequencing technology

a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane

This gene is located in a chromosomal region known to be frequently deleted in patients with neurofibromatosis

Beta-Catenin Polyclonal Antibody, 50ul Organelle Studies USP45 (Ubiquitin carboxyl-terminal hydrolase 45)The protein encoded by CTNNB1 (catenin beta 1) is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete.