PTEN(Phospho Ser380) Polyclonal Antibody, 50ul Antibody Humanization subcellular location:Predominantly in nuclear matrix
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PTEN(Phospho Ser380) Polyclonal Antibody, 50ul Antibody Humanization subcellular location:Predominantly in nuclear matrixThis gene was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency. The protein encoded by this gene is a phosphatidylinositol 3,4,5 trisphosphate 3 phosphatase. It contains a tensin like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases. Unlike most of the protein tyrosine phosphatases, this protein preferentially dephosphorylates phosphoinositide
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