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Chk1(Phospho Ser280) Polyclonal Antibody, 20ul Monoclonal Antibodies a putative transmembrane domain

SKU: 89916290735

4.5
PLN85.00 PLN108.00

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Chk1(Phospho Ser280) Polyclonal Antibody, 20ul Monoclonal Antibodies a putative transmembrane domainThe protein encoded by this gene belongs to the Ser Thr protein kinase family. It is required for checkpoint mediated cell cycle arrest in response to DNA damage or the presence of unreplicated DNA. This protein acts to integrate signals from ATM and ATR, two cell cycle proteins involved in DNA damage responses, that also associate with chromatin in meiotic prophase I. Phosphorylation of CDC25A protein phosphatase by this protein is required for cells

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Description

a putative transmembrane domain

through which this receptor induces the activation of NF-kappa B and MAPK8/JNK

This protein associated with the long isoform of the leptin receptor and with receptor tyrosine kinases for platelet-derived growth factor

This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway

Chk1(Phospho Ser280) Polyclonal Antibody, 20ul Monoclonal Antibodies a putative transmembrane domainThe protein encoded by this gene belongs to the Ser Thr protein kinase family. It is required for checkpoint mediated cell cycle arrest in response to DNA damage or the presence of unreplicated DNA. This protein acts to integrate signals from ATM and ATR, two cell cycle proteins involved in DNA damage responses, that also associate with chromatin in meiotic prophase I. Phosphorylation of CDC25A protein phosphatase by this protein is required for cells

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