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CIR1A Rabbit Polyclonal Antibody, 50ul Vortex Mixer Overexpression of some isoforms of

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CIR1A Rabbit Polyclonal Antibody, 50ul Vortex Mixer Overexpression of some isoforms ofThis gene encodes a WD40 repeat containing protein that is localized to the nucleolus. Mutation of this gene causes North American Indian childhood cirrhosis, a severe intrahepatic cholestasis that results in transient neonatal jaundice, and progresses to periportal fibrosis and cirrhosis in childhood and adolescence. Alternative splicing results in multiple transcript variants.

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Description

Overexpression of some isoforms of the encoded protein inhibits tyrosine kinase activity and results in growth suppression

Homozygous mutations of this gene were observed in primary lymphoma and colon cancer

angiogenesis and cell migration

This cytokine is expressed in B cell lineage cells

CIR1A Rabbit Polyclonal Antibody, 50ul Vortex Mixer Overexpression of some isoforms ofThis gene encodes a WD40 repeat containing protein that is localized to the nucleolus. Mutation of this gene causes North American Indian childhood cirrhosis, a severe intrahepatic cholestasis that results in transient neonatal jaundice, and progresses to periportal fibrosis and cirrhosis in childhood and adolescence. Alternative splicing results in multiple transcript variants.

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