AChR Alpha5 Polyclonal Antibody, 50ul Plasmid Preparation A polymorphism in the terminal

A polymorphism in the terminal exon of this mRNA results in two protein isoforms

This gene is a member of the Krueppel C2H2-type zinc-finger protein family and encodes a zinc finger transcription factor that contains nine Kruppel-type zinc finger domains at the carboxyl terminus

which is found in proteins involved in RAB GTPase signaling and vesicle trafficking

The encoded protein is involved in docking and fusion events at the Golgi apparatus

AChR Alpha5 Polyclonal Antibody, 50ul Plasmid Preparation A polymorphism in the terminalCholinergic receptor nicotinic alpha 5 subunit encoded by CHRNA5 is a nicotinic acetylcholine receptor subunit and a member of a superfamily of ligand gated ion channels that mediate fast signal transmission at synapses. These receptors are thought to be heteropentamers composed of separate but similar subunits. Defects in this gene have been linked to susceptibility to lung cancer type 2 (LNCR2).