SF-1 Polyclonal Antibody, 100ul Mini dry bath disease:Defects in CD40LG are the

disease:Defects in CD40LG are the cause of X-linked immunodeficiency with hyper-IgM type 1 (HIGM1)

These proteins are cleaved by self-catalytic proteolysis into a large extracellular subunit and seven-span transmembrane subunit

This gene encodes a protein containing a lines-like domain

PDE4D encodes one of four mammalian counterparts to the fruit fly 'dunce' gene

SF-1 Polyclonal Antibody, 100ul Mini dry bath disease:Defects in CD40LG are theThe nuclear receptor subfamily 5 group A member 1 encoded by NR5A1 is a transcriptional activator involved in sex determination. The encoded protein binds DNA as a monomer. Defects in this gene are a cause of XY sex reversal with or without adrenal failure as well as adrenocortical insufficiency without ovarian defect.