ETS2 Polyclonal Antibody, 50ul Protein Expression Mutations in the promoter region

Mutations in the promoter region of this gene lead to a diminished response to antileukotriene drugs used in the treatment of asthma and may also be associated with atherosclerosis and several cancers

It is part of a cluster of trypsinogen genes that are located within the T cell receptor beta locus

Multiple transcript variants encoding different isoforms have been found for SIRPB1

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ETS2 Polyclonal Antibody, 50ul Protein Expression Mutations in the promoter regionThis gene encodes a transcription factor which regulates genes involved in development and apoptosis. The encoded protein is also a protooncogene and shown to be involved in regulation of telomerase. A pseudogene of this gene is located on the X chromosome. Alternative splicing results in multiple transcript variants.