Dok-3 Polyclonal Antibody, 50ul General Lab Use Both p105 and p100 are

Both p105 and p100 are proteolytically processed by the proteasome to produce p50 and p52

All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter

and instead have a conserved lysine in subdomain I

While the biological activities of these receptors have yet to be determined

Dok-3 Polyclonal Antibody, 50ul General Lab Use Both p105 and p100 areDok 1, Dok 2 and Dok 3 are members of a class of "docking" proteins which contain multiple tyrosine residues and putative SH2 binding sites. Dok 1 associates with the Ras GTPase activating protein (Ras GAP) upon tyrosine phosphorylation. Dok 2 (also designated p56 Dok) has also been identified as a potential mediator of the effects of p210 Bcr Abl. Dok 3 is an adapter involved in the recruitment of inhibitory molecules and is highly expressed in B