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CD82 Polyclonal Antibody, 100ul Cell Dissociation but lacks cytoplasmic domain

SKU: 85491973370

4.5
USD123.75 USD160.75

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CD82 Polyclonal Antibody, 100ul Cell Dissociation but lacks cytoplasmic domainThis metastasis suppressor gene product is a membrane glycoprotein that is a member of the transmembrane 4 superfamily. Expression of this gene has been shown to be downregulated in tumor progression of human cancers and can be activated by p53 through a consensus binding sequence in the promoter. Its expression and that of p53 are strongly correlated, and the loss of expression of these two proteins is associated with poor survival for prostate

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Description

but lacks cytoplasmic domain

a tyrosine kinase domain

Defects in this gene are a cause of Peters-plus syndrome (PPS)

The encoded protein interacts with anti-apoptotic proteins

CD82 Polyclonal Antibody, 100ul Cell Dissociation but lacks cytoplasmic domainThis metastasis suppressor gene product is a membrane glycoprotein that is a member of the transmembrane 4 superfamily. Expression of this gene has been shown to be downregulated in tumor progression of human cancers and can be activated by p53 through a consensus binding sequence in the promoter. Its expression and that of p53 are strongly correlated, and the loss of expression of these two proteins is associated with poor survival for prostate

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