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p53 Polyclonal Antibody, 100ul[BT-AP06810] Purification as indicated for members 1-3

SKU: 8317063089

4.6
USD123.75 USD155.75

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p53 Polyclonal Antibody, 100ul[BT-AP06810] Purification as indicated for members 1-3TP53 (tumor protein p53) encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in TP53 are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni

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Description

as indicated for members 1-3

and may play a role in regulating the actin cytoskeleton

The protein encoded by this gene is a Rab-GTPase-activating protein| and contains two phopshotyrosine-binding domains (PTB1 and PTB2)| a calmodulin-binding domain (CBD)| a Rab-GTPase domain| and multiple AKT phosphomotifs

This kinase is activated by Rho family of small G proteins and may mediate the Rho-dependent signaling pathway

p53 Polyclonal Antibody, 100ul[BT-AP06810] Purification as indicated for members 1-3TP53 (tumor protein p53) encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in TP53 are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni

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