ITGA2B Rabbit Polyclonal Antibody, 20ul[BT-AP10698] ssDNA Synthesis Multiple alternatively spliced transcript variants

Multiple alternatively spliced transcript variants have been identified in this gene

The encoded protein is the largest subunit of the activating signal cointegrator 1 complex that is involved in DNA repair and resistance to alkylation damage

The protein encoded by EIF3D (eukaryotic translation initiation factor 3 subunit D) is the major RNA binding subunit of the eIF3 complex

which phosphorylates the carboxy-terminal domain (CTD) of the largest subunit of RNA polymerase II

ITGA2B Rabbit Polyclonal Antibody, 20ul[BT-AP10698] ssDNA Synthesis Multiple alternatively spliced transcript variantsThis gene encodes a member of the integrin alpha chain family of proteins. The encoded preproprotein is proteolytically processed to generate light and heavy chains that associate through disulfide linkages to form a subunit of the alpha IIb beta 3 integrin cell adhesion receptor. This receptor plays a crucial role in the blood coagulation system by mediating platelet aggregation. Mutations in this gene are associated with platelet type bleeding