LMTK1 Polyclonal Antibody, 20ul Cell Culture Dishes Loss of function compound heterozygous

Loss of function compound heterozygous mutations in this gene were found in a human patient affected by the Walker-Warburg syndrome (WWS) phenotype

Suppressor of cytokine signaling 2 encoded by SOCS2 interacts with the cytoplasmic domain of insulin-like growth factor-1 receptor (IGF1R) and is thought to be involved in the regulation of IGF1R mediated cell signaling

reverse the reaction (Glowacki et al

This protein is found associated with endosomal membranes

LMTK1 Polyclonal Antibody, 20ul Cell Culture Dishes Loss of function compound heterozygousThe protein encoded by this gene contains a tyrosine kinase domain at the N terminus and a proline rich domain at the C terminus. This gene is induced during apoptosis, and expression of this gene may be a necessary pre requisite for the induction of growth arrest and or apoptosis of myeloid precursor cells. This gene has been shown to produce neuronal differentiation in a neuroblastoma cell line. Two transcript variants encoding different isoforms