TTR mouse Monoclonal Antibody(2B12), 100ul Enzyme Activity Assays Defects in HSPB1 are a

Defects in HSPB1 are a cause of Charcot-Marie-Tooth disease type 2F (CMT2F) and distal hereditary motor neuropathy (dHMN)

A related pseudogene is found on chromosome 3

while Group III includes GRM4

This family of genes encode small ubiquitin-related modifiers that are attached to proteins and control the target proteins' subcellular localization

TTR mouse Monoclonal Antibody(2B12), 100ul Enzyme Activity Assays Defects in HSPB1 are aThis gene encodes transthyretin, one of the three prealbumins including alpha 1 antitrypsin, transthyretin and orosomucoid. Transthyretin is a carrier protein it transports thyroid hormones in the plasma and cerebrospinal fluid, and also transports retinol (vitamin A) in the plasma. The protein consists of a tetramer of identical subunits. More than 80 different mutations in this gene have been reported most mutations are related to amyloid