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Plk1 Polyclonal Antibody, 50ul Vortex Mixer It heterodimerizes with asparagine-linked glycosylation

SKU: 7972946324

4.7
USD162.00 USD203.00

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Plk1 Polyclonal Antibody, 50ul Vortex Mixer It heterodimerizes with asparagine-linked glycosylationSerine threonine protein kinase PLK1 kinase encoded by PLK1 belongs to the CDC5 Polo subfamily. It is highly expressed during mitosis and elevated levels are found in many different types of cancer. Depletion of this protein in cancer cells dramatically inhibited cell proliferation and induced apoptosis; hence, it is a target for cancer therapy.

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Description

It heterodimerizes with asparagine-linked glycosylation 14 homolog to form a functional UDP-GlcNAc glycosyltransferase that catalyzes the second sugar addition of the highly conserved oligosaccharide precursor in endoplasmic reticulum N-linked glycosylation

The protein encoded by this gene belongs the PI3/PI4-kinase family| and is most closely related to ATM| a protein kinase encoded by the gene mutated in ataxia telangiectasia

There are two other brain-specific angiogenesis inhibitor genes

but activates transcription when Ras is present

Plk1 Polyclonal Antibody, 50ul Vortex Mixer It heterodimerizes with asparagine-linked glycosylationSerine threonine protein kinase PLK1 kinase encoded by PLK1 belongs to the CDC5 Polo subfamily. It is highly expressed during mitosis and elevated levels are found in many different types of cancer. Depletion of this protein in cancer cells dramatically inhibited cell proliferation and induced apoptosis; hence, it is a target for cancer therapy.

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