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HJURP Polyclonal Antibody, 50ul Rotator The encoded protein contains twelve

SKU: 77459124875

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HJURP Polyclonal Antibody, 50ul Rotator The encoded protein contains twelveCentromeric protein that plays a central role in the incorporation and maintenance of histone H3 like variant CENPA at centromeres. Acts as a specific chaperone for CENPA and is required for the incorporation of newly synthesized CENPA molecules into nucleosomes at replicated centromeres. Directly binds Holliday junctions.,sequence Translated as Arg.,subcellular location: Localizes in centromeres during late telophase and early G1, when CENPA

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Description

The encoded protein contains twelve putative transmembrane domains and is a plasma integral membrane protein

ANAPC5 encodes a tetratricopeptide repeat-containing component of the anaphase promoting complex/cyclosome (APC/C)

this protein is strongly and selectively expressed in endocrine tissues

the encoded protein may increase the viability of certain cell types through modulation of p53 activity

HJURP Polyclonal Antibody, 50ul Rotator The encoded protein contains twelveCentromeric protein that plays a central role in the incorporation and maintenance of histone H3 like variant CENPA at centromeres. Acts as a specific chaperone for CENPA and is required for the incorporation of newly synthesized CENPA molecules into nucleosomes at replicated centromeres. Directly binds Holliday junctions.,sequence Translated as Arg.,subcellular location: Localizes in centromeres during late telophase and early G1, when CENPA

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