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Rb Polyclonal Antibody, 100ul[BT-AP07685] Monoclonal Antibody Preparation Diseases associated with ZMYM4 include

SKU: 7666208045

4.1
PLN123.75 PLN172.75

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Rb Polyclonal Antibody, 100ul[BT-AP07685] Monoclonal Antibody Preparation Diseases associated with ZMYM4 includeRB transcriptional corepressor 1 encoded by RB1 is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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Description

Diseases associated with ZMYM4 include non-syndromic x-linked intellectual disability

This gene encodes the class A macrophage scavenger receptors

It has been shown in vitro that this protein is able to induce neurite outgrowth in PC12 cells

There are multiple pseudogenes of this gene dispersed throughout the genome

Rb Polyclonal Antibody, 100ul[BT-AP07685] Monoclonal Antibody Preparation Diseases associated with ZMYM4 includeRB transcriptional corepressor 1 encoded by RB1 is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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