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PGD Polyclonal Antibody, 50ul Vortex Mixer The encoded protein is active

SKU: 75853430892

4.0
SEK185.00 SEK234.00

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PGD Polyclonal Antibody, 50ul Vortex Mixer The encoded protein is active6 phosphogluconate dehydrogenase (PGD) is the second dehydrogenase in the pentose phosphate shunt. Deficiency of this enzyme is generally asymptomatic, and the inheritance of this disorder is autosomal dominant. Hemolysis results from combined deficiency of 6 phosphogluconate dehydrogenase and 6 phosphogluconolactonase suggesting a synergism of the two enzymopathies. Several transcript variants encoding different isoforms have been found for this gene.

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Description

The encoded protein is active at acidic pH and is sensitive to the 4-azasteroid inhibitor finasteride

This gene encodes one of five subunits of eukaryotic translation initiation factor 2B (EIF2B)

Death-associated protein 1 acts as a positive mediator of programmed cell death that is induced by interferon-gamma

while defects in this gene are associated with multiple types of cancer

PGD Polyclonal Antibody, 50ul Vortex Mixer The encoded protein is active6 phosphogluconate dehydrogenase (PGD) is the second dehydrogenase in the pentose phosphate shunt. Deficiency of this enzyme is generally asymptomatic, and the inheritance of this disorder is autosomal dominant. Hemolysis results from combined deficiency of 6 phosphogluconate dehydrogenase and 6 phosphogluconolactonase suggesting a synergism of the two enzymopathies. Several transcript variants encoding different isoforms have been found for this gene.

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