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FBN3 Rabbit Polyclonal Antibody, 20ul NGS Oligos The protein encoded by this

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FBN3 Rabbit Polyclonal Antibody, 20ul NGS Oligos The protein encoded by thisThis gene encodes a memebr of the fibrillin protein family. Fibrillins are extracellular matrix molecules that assemble into microfibrils in many connective tissues. This gene is most highly expressed in fetal tissues and its protein product is localized to extracellular microfibrils of developing skeletal elements skin lung kidney and skeletal muscle. This gene is potentially involved in Weill Marchesani syndrome.

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Description

The protein encoded by this gene is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase

The protein may also play a role in endometrial bleeding

Overexpression of this gene in mammary epithelial cells leads to sensitization of the cells to epidermal growth factor and results in a partially transformed phenotype

as a neurotrophic factor that promotes neuronal survival

FBN3 Rabbit Polyclonal Antibody, 20ul NGS Oligos The protein encoded by thisThis gene encodes a memebr of the fibrillin protein family. Fibrillins are extracellular matrix molecules that assemble into microfibrils in many connective tissues. This gene is most highly expressed in fetal tissues and its protein product is localized to extracellular microfibrils of developing skeletal elements skin lung kidney and skeletal muscle. This gene is potentially involved in Weill Marchesani syndrome.

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