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PARP8 Polyclonal Antibody, 20ul Gloves Subfamily A contains 12 genes|

SKU: 73078627734

4.6
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PARP8 Polyclonal Antibody, 20ul Gloves Subfamily A contains 12 genes|Catalytic activity: NAD(+) + (ADP D ribosyl)(n) acceptor = nicotinamide + (ADP D ribosyl)(n+1) acceptor.,PTM: Phosphorylated upon DNA damage, probably by ATM or ATR.,sequence Contaminating sequence. Potential poly A sequence.,Contains 1 PARP catalytic domain.,

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Description

Subfamily A contains 12 genes| subfamily B contains 7 genes and 2 pseudogenes| and the more distantly related subfamily C contains 3 genes

autosomal dominant or X-linked inheritance

Defects in VCL are the cause of cardiomyopathy dilated type 1W

The encoded protein is also a candidate tumor suppressor protein| and aberrant promoter methylation of this gene may play a role in cervical cancer

PARP8 Polyclonal Antibody, 20ul Gloves Subfamily A contains 12 genes|Catalytic activity: NAD(+) + (ADP D ribosyl)(n) acceptor = nicotinamide + (ADP D ribosyl)(n+1) acceptor.,PTM: Phosphorylated upon DNA damage, probably by ATM or ATR.,sequence Contaminating sequence. Potential poly A sequence.,Contains 1 PARP catalytic domain.,

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