Desmin Monoclonal Antibody(1B12), 50ul Antibodies the encoded protein contains 2-43

the encoded protein contains 2-43 copies of kringle-type domains

This gene encodes a member of a group of membrane-anchored chymotrypsin (S1)-like serine proteases

PTM:Phosphorylated on Ser-13 in mitosis

function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation

Desmin Monoclonal Antibody(1B12), 50ul Antibodies the encoded protein contains 2-43This gene encodes a muscle specific class III intermediate filament. Homopolymers of this protein form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane. Mutations in this gene are associated with desmin related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies.