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MACC1 Polyclonal Antibody, 100ul Cell Senescence Inhibits HSPA8/HSC70 ATPase and chaperone

SKU: 70565250486

4.6
USD141.00 USD172.00

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MACC1 Polyclonal Antibody, 100ul Cell Senescence Inhibits HSPA8/HSC70 ATPase and chaperoneMACC1 is a key regulator of the hepatocyte growth factor (HGF; MIM 142409) HGF receptor (HGFR, or MET; MIM 164860) pathway, which is involved in cellular growth, epithelial mesenchymal transition, angiogenesis, cell motility, invasiveness, and metastasis. Expression of MACC1 in colon cancer (MIM 114500) specimens is an independent prognostic indicator for metastasis formation and metastasis free survival (Stein et al. 2009 [PubMed: 19098908]).

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Description

Inhibits HSPA8/HSC70 ATPase and chaperone activities Diseases associated with HSPH1 include hepatitis d

The CD27 antigen cytoplasmic tail binds to the N-terminus of this protein

This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription

rapid growth

MACC1 Polyclonal Antibody, 100ul Cell Senescence Inhibits HSPA8/HSC70 ATPase and chaperoneMACC1 is a key regulator of the hepatocyte growth factor (HGF; MIM 142409) HGF receptor (HGFR, or MET; MIM 164860) pathway, which is involved in cellular growth, epithelial mesenchymal transition, angiogenesis, cell motility, invasiveness, and metastasis. Expression of MACC1 in colon cancer (MIM 114500) specimens is an independent prognostic indicator for metastasis formation and metastasis free survival (Stein et al. 2009 [PubMed: 19098908]).

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