SMG9 Polyclonal Antibody, 100ul Isothermal Amplification Mutations in the promoter region

Mutations in the promoter region of this gene lead to a diminished response to antileukotriene drugs used in the treatment of asthma and may also be associated with atherosclerosis and several cancers

which implicated the role of

This protein (tumor necrosis factor superfamily member 13) is a ligand for TNFRSF17/BCMA

Although its function is unknown| the observation that this gene is conserved in the mouse implies it has some function

SMG9 Polyclonal Antibody, 100ul Isothermal Amplification Mutations in the promoter regionThis gene encodes a regulatory subunit of the SMG1 complex, which plays a critical role in nonsense mediated mRNA decay (NMD). Binding of the encoded protein to the SMG1 complex kinase scaffold protein results in the inhibition of its kinase activity. Mutations in this gene cause a multiple congenital anomaly syndrome in human patients, characterized by brain malformation, congenital heart disease and other features.