Nibrin Polyclonal Antibody, 50ul[BT-AP06020] Recombinant Protein Expression suggesting that this kinase may

suggesting that this kinase may serve as an intermediate in the response to cellular stress

Mutations inCSF1R have been associated with a predisposition to myeloid malignancy

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suggesting that it may have a role in transcription regulation

Nibrin Polyclonal Antibody, 50ul[BT-AP06020] Recombinant Protein Expression suggesting that this kinase mayMutations in NBN are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. Nibrin is a member of the MRE11 RAD50 double strand break repair complex which consists of 5 proteins. NBN product is thought to be involved in DNA double strand break repair and DNA damage induced checkpoint activation.