Tyro3 Monoclonal Antibody, 100ul[BT-MCA1263] Filtration May also regulate ESR1 levels

May also regulate ESR1 levels indirectly via a PKC-AKT-FOXO3 pathway where it decreases the activity of PKC and the phosphorylation of AKT

Alternatively spliced transcript variants encoding distinct proteins have been described

Alternate splicing of KLK11 results in multiple transcript variants encoding distinct isoforms which are differentially expressed

This gene encodes a multi-pass membrane protein that functions as a voltage gated cation channel

Tyro3 Monoclonal Antibody, 100ul[BT-MCA1263] Filtration May also regulate ESR1 levelsThe gene is part of a 3 member transmembrane receptor kinase receptor family with a processed pseudogene distal on chromosome 15. The encoded protein is activated by the products of the growth arrest specific gene 6 and protein S genes and is involved in controlling cell survival and proliferation, spermatogenesis, immunoregulation and phagocytosis. The encoded protein has also been identified as a cell entry factor for Ebola and Marburg viruses.