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4.1R Polyclonal Antibody, 20ul Protein Expression Easy to switch between manualThe erythrocyte membrane protein band 4. encoded by EPB41, together with spectrin and actin, constitute the red cell membrane cytoskeletal network. This complex plays a critical role in erythrocyte shape and deformability. Mutations in this gene are associated with type 1 elliptocytosis (EL1). Alternatively spliced transcript variants encoding different isoforms have been described for this gene.