Stat2 (Acetyl Lys384) Rabbit Polyclonal Antibody, 50ul In vitro Assessment TACC3 encodes a member of

TACC3 encodes a member of the transforming acidic colied-coil protein family

Required for RNA polymerase III-mediated transcription

Alternative coreceptor with CD4 for HIV-1 infection

MIB1 (mindbomb E3 ubiquitin protein ligase 1) encodes a protein containing multiple ankyrin repeats and RING finger domains that functions as an E3 ubiquitin ligase

Stat2 (Acetyl Lys384) Rabbit Polyclonal Antibody, 50ul In vitro Assessment TACC3 encodes a member ofSignal transducer and activator of transcription that mediates signaling by type I IFNs (IFN alpha and IFN beta). Following type I IFN binding to cell surface receptors Jak kinases (TYK2 and JAK1) are activated leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize associate with ISGF3G IRF 9 to form a complex termed ISGF3 transcription factor that enters the nucleus. ISGF3 binds to the IFN stimulated response