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TM156 Rabbit Polyclonal Antibody, 50ul ssDNA Synthesis F12 encodes coagulation factor XII

SKU: 56617153239

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TM156 Rabbit Polyclonal Antibody, 50ul ssDNA Synthesis F12 encodes coagulation factor XII

Store: firemistltd.co.uk · Domain: firemistltd.co.uk

Description

F12 encodes coagulation factor XII which circulates in blood as a zymogen

Mutations in this gene are the cause of hypogonadotropic hypogonadism 20 with or without anosmia

The protein binds to the SH3 domains of several proteins including the ABL1 and SYK protein tyrosine kinases | and functions as a cytoplasmic adaptor protein to positively regulate transcriptional activity in T| natural killer (NK)| and basophilic cells

Multiple alternatively spliced transcript variants for this gene have been described but only one has had its full-length nature determined

TM156 Rabbit Polyclonal Antibody, 50ul ssDNA Synthesis F12 encodes coagulation factor XII

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