MC2-R Polyclonal Antibody, 50ul Drug Development and Evaluation This enzyme is involved in

This enzyme is involved in the metabolism of approximately half the drugs in use today

A related pseudogene is located on chromosome 9

The protein encoded by this gene belongs to the dystrobrevin subfamily of the dystrophin family

BRE is upregulated in several types of cancer

MC2-R Polyclonal Antibody, 50ul Drug Development and Evaluation This enzyme is involved inMC2R encodes one member of the five member G protein associated melanocortin receptor family. Melanocortins (melanocyte stimulating hormones and adrenocorticotropic hormone) are peptides derived from pro opiomelanocortin (POMC). MC2R is selectively activated by adrenocorticotropic hormone, whereas the other four melanocortin receptors recognize a variety of melanocortin ligands. Mutations in MC2R can result in familial glucocorticoid deficiency.