RPTOR Polyclonal Antibody, 50ul Cellular Function Assays Mutations in this gene result

Mutations in this gene result in pontocerebellar hypoplasia type 2

This protein found to be tightly associated with membrane-bound ribosomes| either directly or through adaptor proteins

Inhibits HSPA8/HSC70 ATPase and chaperone activities Diseases associated with HSPH1 include hepatitis d

This protein may function as a transcriptional co-activator/repressor that controls the growth and differentiation of specific cell types during embryonic development and tissue regeneration

RPTOR Polyclonal Antibody, 50ul Cellular Function Assays Mutations in this gene resultThis gene encodes a component of a signaling pathway that regulates cell growth in response to nutrient and insulin levels. The encoded protein forms a stoichiometric complex with the mTOR kinase, and also associates with eukaryotic initiation factor 4E binding protein 1 and ribosomal protein S6 kinase. The protein positively regulates the downstream effector ribosomal protein S6 kinase, and negatively regulates the mTOR kinase. Multiple transcript