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Smad7 (Acetyl Lys70) Rabbit Polyclonal Antibody, 50ul Cell Culture Dishes The product of this gene

Smad7 (Acetyl Lys70) Rabbit Polyclonal Antibody, 50ul Cell Culture Dishes The product of this gene

Name: Smad7 (Acetyl Lys70) Rabbit Polyclonal Antibody, 50ul Cell Culture Dishes The product of this gene
Brand: firemistltd.co.uk
SKU: 52280033989
Price: 185.00 USD
Availability: InStock
Rating: 4.5472 (18 reviews)

SKU: 52280033989

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Smad7 (Acetyl Lys70) Rabbit Polyclonal Antibody, 50ul Cell Culture Dishes The product of this geneThe protein encoded by this gene is a nuclear protein that binds the E3 ubiquitin ligase SMURF2. Upon binding this complex translocates to the cytoplasm where it interacts with TGF beta receptor type 1 (TGFBR1) leading to the degradation of both the encoded protein and TGFBR1. Expression of this gene is induced by TGFBR1. Variations in this gene are a cause of susceptibility to colorectal cancer type 3 (CRCS3). Several transcript variants encoding

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Description

The product of this gene binds to chemokine receptors CCR4 and CCR8

PTM:Phosphorylated upon DNA damage

and thus mediates immediate-early gene expression in response to various cell stimuli

as Endophilin I is ex- pressed only in the brain

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