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PTEN Polyclonal Antibody, 50ul[BT-AP07470] Purification Mutations in this gene result

SKU: 5215217003

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PTEN Polyclonal Antibody, 50ul[BT-AP07470] Purification Mutations in this gene resultPTEN was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency. Pphosphatase and tensin homolog encoded by PTEN is a phosphatidylinositol 3,4,5 trisphosphate 3 phosphatase. It contains a tensin like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases. Unlike most of the protein tyrosine phosphatases, t phosphatase and tensin homolog preferentially

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Description

Mutations in this gene result in autosomal dominant hereditary thrombophilia

Gene Ontology (GO) annotations related to OLFML2B include extracellular matrix binding

Probable anchoring protein which tethers the nucleus to the cytoskeleton by binding PLEC which can associate with the intermediate filament system

They may participate in fatty acyl and cholesterol ester metabolism

PTEN Polyclonal Antibody, 50ul[BT-AP07470] Purification Mutations in this gene resultPTEN was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency. Pphosphatase and tensin homolog encoded by PTEN is a phosphatidylinositol 3,4,5 trisphosphate 3 phosphatase. It contains a tensin like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases. Unlike most of the protein tyrosine phosphatases, t phosphatase and tensin homolog preferentially

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