Fos B Polyclonal Antibody, 50ul Low retention tips Mutations in this gene cause

Mutations in this gene cause Griscelli syndrome type-1 (GS1)

The encoded protein (B-cell receptor-associated protein 31) is a multi-pass transmembrane protein of the endoplasmic reticulum that is involved in the anterograde transport of membrane proteins from the endoplasmic reticulum to the Golgi and in caspase 8-mediated apoptosis

This gene encodes a member of the annexin family of evolutionarily conserved Ca2+ and phospholipid binding proteins

It functions in the cardiovascular and central nervous systems

Fos B Polyclonal Antibody, 50ul Low retention tips Mutations in this gene causeThe Fos gene family consists of 4 members: fOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP 1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. Alternatively spliced transcript variants encoding different isoforms have been found for FOSB.