UBE2D2 Polyclonal Antibody, 100ul Deep Well Plates This gene is located within

This gene is located within a chromosomal region that shows loss of heterozygosity in some bladder cancers

The protein encoded by this gene functions together with DNA ligase IV and the DNA-dependent protein kinase in the repair of DNA double-strand breaks

Defects in CYB5A are a cause of type IV hereditary methemoglobinemia

a key step in the catabolism of tyrosine

UBE2D2 Polyclonal Antibody, 100ul Deep Well Plates This gene is located withinRegulated degradation of misfolded, damaged or short lived proteins in eukaryotes occurs via the ubiquitin (Ub) proteasome system (UPS). An integral part of the UPS system is the ubiquitination of target proteins and covalent linkage of Ub containing proteins to form polymeric chains, marking them as targets for 26S proteasome mediated degradation. Ubiquitination of proteins is mediated by a cascade of enzymes which includes E1 (ubiquitin activating),