Nectin 3 Polyclonal Antibody, 50ul[BT-AP05869] Bio-Reaction Tube This MAGEA gene encodes a

This MAGEA gene encodes a protein that is C-terminally truncated compared to other family members

May function in transmigration of leukocytes through epithelial and endothelial tissues

E3 ubiquitin protein ligase is able to interact with the human homolog of yeast Rad6 protein through a conserved ring-finger motif

Mutations in POLE have been associated with colorectal cancer 12 and facial dysmorphism

Nectin 3 Polyclonal Antibody, 50ul[BT-AP05869] Bio-Reaction Tube This MAGEA gene encodes aPVRL3 encodes a member of the nectin family of proteins, which function as adhesion molecules at adherens junctions. This family member interacts with other nectin like proteins and with afadin, a filamentous actin binding protein involved in the regulation of directional motility, cell proliferation and survival. PVRL3 plays a role in ocular development involving the ciliary body. Mutations in this gene are believed to result in congenital ocular