MITF Polyclonal Antibody, 50ul Glassware Sets The synthesis of non-AUG initiated

The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas

The encoded protein is highly basic| contains a PAZ domain and a PIWI domain| and may play a role in short-interfering-RNA-mediated gene silencing

A mutation in this gene has been associated with bilateral nasolacrimal duct obstruction (LCDD)

Alternate use of an in-frame upstream non-AUG (CUG) translation initiation codon| and a downstream AUG codon| results in two isoforms

MITF Polyclonal Antibody, 50ul Glassware Sets The synthesis of non-AUG initiatedMITF encodes microphthalmia associated transcription factor that contains both basic helix loop helix and leucine zipper structural features. It regulates the differentiation and development of melanocytes retinal pigment epithelium and is also responsible for pigment cell specific transcription of the melanogenesis enzyme genes. Heterozygous mutations in the this gene cause auditory pigmentary syndromes, such as Waardenburg syndrome type 2 and Tietz